For years, Interpol agent Mike Whittier is after 'The Organization', a shady international network with tentacles everywhere, specialized in expert killings. He finds the Russian secret police FSB's Moscow officer Yuri Marklov far from cooperative in pursuit of Organization agent 47, a first-grade, genetically-engineered murder machine, whom West-friendly statesman Mikhail Belicoff's mob brother Udre hired to kill Michael, having a double in place to take his place, officially unnoticed. His atypical feelings for local Nika Boronina complicate 47's life, which is on the line as disloyal result of dirty games like double crossing.